Omics Intelligence for Health
Omics Intelligence for Health Lab
We integrate human genetics, multi-omics, clinical data, and artificial intelligence to make personalized medicine the standard of care for cardiometabolic and age-related chronic conditions.
Personalized medicine as the new standard of care
Cardiometabolic and age-related chronic diseases remain the leading causes of death worldwide, yet most patients are still treated according to population averages rather than their own biology.
Our group builds the evidence and the tools to change this. We combine large-scale human genetics with proteomic, metabolomic, and clinical data, and we use machine learning and AI agents to turn these data into decisions: who is at risk, which mechanism drives their disease, and which treatment will work for them.
The lab sits within the Cardiovascular Research Center at Massachusetts General Hospital, the Mass General Brigham Heart and Vascular Institute, Harvard Medical School, and the Broad Institute of MIT and Harvard, an ecosystem that connects discovery science directly to patient care.
Five research programs
Mechanistic clinical trials
Omics-augmented trials run within MGH and Harvard-affiliated hospitals, designed to reveal not only whether a treatment works but how.
Learn more → 02Agentic biology
AI agents for scientific discovery, with several studies underway in partnership with Google DeepMind and other collaborators.
Learn more → 03Drug development
Target discovery with whole genome sequencing, machine learning, and biological digital twins, validated with experimental collaborators.
Learn more → 04Clinical informatics
Genetics and omics brought into EHR, laboratory, and imaging data to personalize risk prediction, diagnosis, and treatment.
Learn more → 05Precision public health
Population genetics made part of how public health works, in close collaboration with the Global Burden of Disease study.
Learn more → JOINWork with us
We are recruiting postdoctoral fellows, students, and research staff who want to build the next generation of precision medicine.
Open positions →Featured publications
Main-authored papers. Bold marks the principal investigator. * equal contribution (co-first author). † co-corresponding or co-senior author.
Lab news
Min Seo Kim, MD, MS
Incoming Assistant Professor, Harvard Medical School
Investigator, Cardiovascular Research Center at Massachusetts General Hospital & Mass General Brigham Heart and Vascular Institute
Collaborating Member, Broad Institute of MIT and Harvard
Min Seo is a physician-scientist whose research integrates human genetics, multi-omics, computational biology, and AI to improve the prediction, prevention, and treatment of cardiometabolic and age-related chronic conditions. He trained at the Broad Institute of MIT and Harvard under the joint mentorship of Patrick T. Ellinor and Akl C. Fahed. His mission is to make personalized medicine the standard of care by turning omics data into decisions that reach both patients and populations.
We are recruiting
If you are a student, a prospective postdoctoral fellow, or a collaborator who shares our goal of making personalized medicine the standard of care, we would like to hear from you.